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Gary Bassell, Ph.D.Department of Neurology Our laboratory is investigating disease mechanisms and novel therapeutic strategies for spinal muscular atrophy, amyotrophic lateral sclerosis, nerve and spinal cord injuries. |
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Ranjita Betarbet, Ph.D.Department of Neurology, Cognitive Division My research interests are in pathogenesis, progression and spread of neurodegenerative diseases including Parkinson’s and Alzheimer’s diseases. |
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Brian J. Ciliax, Ph.D.Department of Neurology My lab focuses on the development of novel agents to image the neuropathology of Alzheimer's Disease. |
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Marla Gearing, Ph.D.Department of Pathology I investigate the pathogenesis of and neuropathologic overlap among neurodegenerative diseases. |
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Jonathan Glass, M.D.Department of Neurology I am focused on the pathogenesis and prevention of axonal degeneration as it applies to neurodegenerative diseases. |
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Ellen Hess, Ph.D.Department of Pharmacology Our laboratory uses molecular, genetic, anatomical and behavioral approaches to determine the contribution of the basal ganglia and cerebellum to normal movements and movement disorders. Our specific interest is dystonia, a movement disorder caused by dysfunction of the basal ganglia, the cerebellum or both. |
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William Hu, M.D., Ph.D.Department of Neurology My laboratory focuses on developing biochemical markers for neurodegenerative disorders including frontotemporal lobar degenerations and Alzheimer’s disease, and to characterize the relationship between these biomarkers and brain pathology. |
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H.A. Jinnah, M.D., Ph.D.Departments of Neurology and Human Genetics My laboratory group focusses on both clinical aspects and the neurobiological basis for dystonia, a movement disorder characterized by involuntary twisting movements and posturing. |
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Richard Kahn, Ph.D.Department of Biochemistry Members of the Kahn lab conduct basic research into the mechanisms of cell regulation by GTP binding proteins, particularly the Arf family of 21 kDa GTPases and their associated partners. |
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Thomas Kukar, Ph.D.Department of Pharmacology My lab studies the development of new therapeutic approaches for treating Alzheimer’s disease, Frontotemporal dementia, and related neurodegenerative disorders. |
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James Lah, M.D., Ph.D.Department of Neurology My research interests focus on understanding basic pathogenic mechanisms in Alzheimer‚s disease, which will enhance translation of research advances into therapeutic applications. |
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Allan Levey, M.D., Ph.D.Department of Neurology My research interests focus on understanding basic pathogenic mechanisms in Alzheimer's disease, which will enhance translation of research advances into therapeutic applications. |
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Lian Li, Ph.D.Department of Pharmacology My lab studies the molecular pathogenic mechanisms of Parkinson's Disease and other age-related neurodegenerative disorders. |
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Zixu Mao, M.D., Ph.D.Departments of Neurology and Pharmacology My lab studies the molecular and cellular mechanisms of neuronal stress response. |
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Gary Miller, Ph.D.Department of Environmental Health Dr. Miller's laboratory is focused on identifying the underlying cause of Parkinson's disease with an emphasis on environmental factors. His group is also developing novel animal models and therapies for the disease. |
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Timothy Read, Ph.D.Departments of Medicine, Infectious Disease, and Human Genetics
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Kerry Ressler, M.D., Ph.D.Department of Psychiatry The primary objective of the work in the Ressler lab is to utilize the power of molecular genetics to understand the molecular biology, neural circuitry, and behavioral biology of fear and its extinction in mouse models and in humans with disorders of fear regulation. |
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Michael R. Rossi, Ph.D.Department of Radiation Oncology My research uses next generation sequencing technologies to identify novel mechanisms of disease, particularly for adult and pediatric brain tumors. |
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Wilfried Rossoll, Ph.D.Department of Cell Biology My main research interest is the biological role of mRNA transport and local translation in motor neurons and their dysfunction in neurodegenerative diseases, such as spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). |
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Subhabrata Sanyal, Ph.D.Department of Cell Biology Our lab uses Drosophila as a genetic model organism to explore molecular mechanisms underlying neuronal plasticity, stress and sleep. We use a number of techniques such as electrophysiology, confocal microscopy, genetic analysis, molecular biology and behavioral assays. |
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Department of Biochemistry We use a quantitative mass spectrometry approach to define protein aggregation and post-translational modification events observed in neurodegenerative disease. |
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Malu G. Tansey, Ph.D.Department of Physiology My lab studies the role and regulation of neuroinflammation and immune system function in CNS function in health and disease with particular interest in neurodegenerative diseases. |
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Steve Traynelis, Ph.D.Department of Pharmacology We explore the structure and function of glutamate receptors with the dual goal of understanding better their contribution to neurodegenerative processes as well as identifying novel therapeutic strategies by which regulation of glutamate receptors might be neuroprotective. We also evaluate regulation of microglial function in resting and neuroinflammatory conditions by G-protein coupled receptors. |
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Lary C. Walker, Ph.D.Department of Neurology and Yerkes National Primate Research Center I am interested in the basic mechanisms underlying Alzheimer’s disease. |
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Thomas Wingo, M.D.Department of Neurology My laboratory focuses on identifying genetic causes at work in families with Alzheimer’s disease. The goal of our work is to ultimately gain a more complete understanding of the pathogenesis of Alzheimer’s disease by identifying new genetic loci that contribute to disease. |
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Manuel Yepes, M.D.Department of Neurology Our work focuses on the study of the mechanisms leading to the development of cell death, neuroinflammation and increased blood-brain barrier permeability in the ischemic brain. |
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James Zheng, Ph.D.Departments of Cell Biology and Neurology Our laboratory employs state-of-art imaging techniques in combination with molecular and cell biology to study the signal transduction and cytoskeletal mechanisms underlying neural development and disorders. Our current research focuses on three areas: axon guidance and regeneration, synapse plasticity, and neuronal trafficking. |